A .Vogel Anti-Stress St. John’s Wort

NPN 80008387
Traditionally used as sedative for relief of restlessness or nervousness. Helps to treat symptoms of sleep disorders.

A.Vogel Anti-Stress is a proven remedy to relieve restlessness.

A.Vogel Anti-Stress

• Sedative for relief of restlessness and nervousness
• Helps to treat symptoms of sleep disorders.
• Organic cultivation certified by Bio Suisse
• Sugar-, gluten- and lactose-free

Composition

Dosage

Adults: Take 1 tablet, 3 times daily with water, 30 minutes before meals.Duration of use: May be used for up to 6 weeks.

Historical overview

Actions and pharmacology

Numerous studies confirm St. Johns Worts antidepressant effect. Its active ingredients are mainly hyperforin, hypericin and pseudohypericin. Hyperforin seems to be the most active molecule for the relief of depression and mood disorders: it inhibits serotonin reuptake (the same as antidepressant medications like Zoloft®). However, St. Johns Wort has a more global action because it also reduces the reuptake of many other neurotransmitters like GABA, L glutamate, norepinephrin and dopamin. It also has an inhibiting effect on serotonin-specific receptors: 5 HT3, 5 HT4 and, to a lesser degree, 5 HT2. These effects increase the neurotransmitters bioavailability and promote mood-improvement.(1) A few studies have also noted an in vitro activity against some viruses (herpes, polio, hepatitis C, retrovirus, cytomegalovirus, etc.) and bacteria (some gram-negative and gram-positive bacteria). The clinical significance of this is yet to be demonstrated.(1) The German Commission E acknowledges its benefits in cases of: psycho-vegetative disturbances, depressive moods, anxiety and nervous unrest.(2)

Institut Anca Anca Cercel N.D.
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